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Study shows: PanTum Detect® detects patients with rhabdomyosarcoma.

Tübingen researchers show: PanTum Detect® blood test detects increased TKTL1 and DNaseX (Apo10) levels in children with neuroblastoma.

Study shows: PanTum Detect® test paves the way for the targeted use of imaging procedures for early cancer detection.

Xie, C., Wang, S., Guo, C. et al. Apo10 and TKTL1 in blood macrophages as biomarkers for differentiating lung cancer from benign lung lesions: a comparative study with conventional biomarkers. | Cellular Oncology 2023

Burg S.; Smeets R.; Gosau M.; Failing K.; Grust A.: Case Report: Early detection of lung carcinoid in an asymptomatic individual by blood-test initiated PET-CT imaging. | Frontiers in Oncology 2023

Li Y.; Xu C.; Wang B.; Xu F.; Ma F. et al.: Proteomic characterization of gastric cancer response to chemotherapy and targeted therapy reveals new therapeutic strategies. | nature communications 2022

Pinson A.; Xing L.; Xinnan L.; Namba T.; Kalebic N; Peters J. et al.: Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals. | Science 2022

Liu Q.; Fangming Z.; Xinnan L.; Ying L.; Ke Y.; Na T.; et al.: Non-oxidative pentose phosphate pathway controls regulatory T cell function by integrating metabolism and epigenetics. | nature metabolism 2022

Hao S.; Qingfei, M.; Huihui S.; Yunkuo L.; Yao L.; et al.: The role of transketolase in human cancer progression and therapy. | Elsevier 2022

Urla, C.; Stagno, M.J.; Schmidt, A.; Handgretinger, R.; Fuchs, J.; Warmann, S.W.; Schmid, E. Epitope Detection in Monocytes (EDIM) As a New Method of Liquid Biopsy in Pediatric Rhabdomyosarcoma. | Biomedicines 2022, 10, 1812.

Burg S, Grust ALC, Feyen O, Failing K, Banat G-A, Coy JF, et al. Blood-Test Based Targeted Visualization Enables Early Detection of Premalignant and Malignant Tumors in Asymptomatic Individuals. | Journal of Clinical and Medical Images. 2022;6.

Stagno M, Schmidt A, Bochem J, et al. Epitope detection in monocytes (EDIM) for liquid biopsy including identification of GD2 in childhood neuroblastoma—a pilot study. | British Journal of Cancer. 2022;7.

Baptista I, Karakitsou E, Cazier J-B, Günther UL, Marin S, Cascante M. TKTL1 Knockdown Impairs Hypoxia-Induced Glucose-6-phosphate Dehydrogenase and Glyceraldehyde-3-phosphate Dehydrogenase Overexpression. | Int J Mol Sci. 2022;23:3574.

Li M, Zhao X, Yong H, Xu J, Qu P, Qiao S, et al. Transketolase promotes colorectal cancer metastasis through regulating AKT phosphorylation. | Cell Death Dis. 2022;13:99.

Niu C, Qiu W, Li X, Li H, Zhou J, Zhu H. Transketolase Serves as a Biomarker for Poor Prognosis in Human Lung Adenocarcinoma. | J Cancer. 2022;13:2584–93.

Zhang L, Huang Z, Cai Q, Zhao C, Xiao Y, Quan X, et al. Inhibition of Transketolase Improves the Prognosis of Colorectal Cancer. | Front Med. 2022;9:837143.